师资队伍

杨恺

                姓名:杨恺
                职称:副教授
                部门:软凝聚态物理及交叉研究中心
                联系方式:
                0512- 65220239电子邮箱:yangkai@suda.edu.cn

个人简历:

2000年毕业于云南大学物理系数理基地班,获理学学士学位;2003年毕业于云南大学材料科学与工程系,获理学硕士学位;2009年毕业于南京大学物理学系,获理学博士学位。2003年至2010年在云南民族大学物理与电子电气信息工程学院工作;201011月加入苏州大学物理科学与技术学院/软凝聚态物理及交叉研究中心,特聘副教授,硕士生导师。

主要从事细胞膜生物物理和生命软物质自组装方面的研究。目前已在Nature NanotechnologyNanoscaleBiomaterials等国际知名杂志发表学术论文10余篇其中,关于几何纳米粒子入侵细胞膜方面的研究结果被Nature China和科学时报作为Research Highlights 进行评述;关于几何纳米粒子内吞机制的部分研究结果入选Biomaterials Images 2012 poster;有关生物膜形变、分裂机制方面的评述文章入选了《Soft Matter》杂志201111“Top Ten most-read Soft Matter articles”

获奖、荣誉和学术兼职:

1. 全国优秀博士学位论文提名奖2012年)

2. 南京微结构固体物理国家重点实验室研究生优秀成果奖

3. 苏州市高等院校、科研院所紧缺高层次人才

任教课程:

1. 软物质前沿

2. 软凝聚态物理导论

3. 医用物理

研究领域:      

1. 细胞的内吞现象及其物理机制.

2. 纳米-生物相互作用(Nano-Bio interaction);纳米药物载体的设计纳米粒子的细胞毒性.

3. 生物膜蛋白体系的自组织行为生命软物质的自组装行为.

4. 软物质体系的分子模拟.

基金项目:

1. 中国国家自然科学基金面上项目(主持)

2. 中国国家自然科学基金青年项目(主持)

3. 教育部科学技术研究重点项目(主持)

4. 江苏省自然科学基金面上项目(主持)

5. 苏州大学人才引进启动经费

代表性论著、研究成果:

1. Yu-jiang Dou, Jing-liang Li, Bing Yuan*, Kai Yang*. Lipid merging, protrusion and vesicle release triggered by shrinking/swelling of poly(N-isopropylacrylamide) microgel particles.Appl. Surf. Sci., 2014, 296(30), 95-99(*Corresponding author).

2. Nai-yan Lu, Bing Yuan*, Kai Yang*. Nonspecific adsorption of charged mesoporousnanoparticles on supported thiol/lipidhybrid bilayers. Acta Phys. Sin., 2013, 62 (17), 178701(*Corresponding author).

3. Nai-yan Lu, Kai Yang, Jing-liang Li, Yuyan Weng, Bing Yuan, and Yu-qiang Ma, Controlled Drug Loading and Release of a Stimuli-responsive Lipogel Consisting of Poly(N-isopropylacrylamide) Particle and Lipids, J. Phys. Chem. B, 2013, 117(33), 9677–9682.

4. Jiao-jiao Liu, Nai-yan Lu, Jing-liang Li, Yu-yan Weng, Bing Yuan*, Kai Yang*, and Yu-qiang Ma. Influence of Surface Chemistry on Particle Internalization into Giant Unilamellar Vesicles. Langmuir, 2013, 29 (25), 8039–8045(*Corresponding author).

5. Kai Yang, Bing Yuan, Yu-qiang Ma. Influence of geometric nanoparticle’s rotation on cellular internalization Process. Nanoscale, 2013, 5, 7998–8006.

6. Nai-yan Lu, Kai Yang, Jing-liang Li, Bing Yuan, and Yu-qiang Ma, Vesicle Deposition and Subsequent Membrane-melittin Interactions on Different Substrates: a QCM-D Experiment, BBA-Biomembranes, 2013, 1828:1918-1925.  

7. Nai-yan Lu, Kai Yang, Bing Yuan and Yu-qiang Ma, Molecular Response and Cooperative Behavior during the Interactions of Melittin with a Membrane: Dissipative Quartz Crystal Microbalance Experiments and Simulations,J. Phys. Chem. B, 2012, 116:9432-9438.

8. Kai Yang, Bing Yuan, Yu-qiang Ma. Curvature Changes of Bilayer Membranes Studied by Computer Simulations. J. Phys. Chem. B, 2012, 116:7196-7202.

9. Ye Li, Tong-tao Yue, Kai Yang*, Xian-ren Zhang. Molecular modeling of the relationship between nanoparticle shape anisotropy and endocytosis kinetics. Biomaterials, 2012, 33:4965-4973 (*Corresponding author).

10. Kai Yang, Yu-qiang Ma. Computer simulations of fusion, fission and shape deformation in lipid membranes. Soft Matter, 2012, 8:606-618 (Invited Review).

11. Kai Yang, Yu-qiang Ma. Wrapping and Internalization of Nanoparticles by Lipid Bilayers: a Computer Simulation Study. Aust. J. Chem., 2011, 64:894–899.

12. Xi Shao, Kai Yang, Yu-qiang Ma. A dissipative particle dynamics study on the morphologies of H-shaped block copolymers in solvent. Int. J. Mod. Phys. B, 2011, 25(6):843–850.

13. Kai Yang, Yu-qiang Ma. Computer Simulation of the Translocation of Nanoparticles with Different Shapes Across a Lipid Bilayer. Nature Nanotechnology, 2010, 5: 579-583 (Highlighted by Nature China).

14. Kai Yang, Yu-qiang Ma. Computer Simulations of Vesicle Fission Induced by External Amphipathic Inclusions. J. Phys. Chem. B, 2009, 113: 1048-1057.

15. Kai Yang, Xi Shao, Yu-qiang Ma. Shape deformation and fission route of the lipid domain in a multicomponent vesicle. Phys. Rev. E, 2009, 79: 051924 (Highlighted by PRE Kaleidoscope).


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